Ceftriaxone is a third-generation cephalosporin antibiotic with broad-spectrum bactericidal activity. It interferes with the bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis and bacterial death. Ceftriaxone is effective against both Gram-positive and Gram-negative bacteria.
Tazobactam is a β-lactamase inhibitor that protects ceftriaxone from degradation by β-lactamase enzymes produced by certain bacteria. This enhances the effectiveness of ceftriaxone against resistant organisms, including those that produce β-lactamase.
The combination of ceftriaxone and tazobactam provides an extended spectrum of activity, especially against resistant pathogens.
Indications: This veterinary injection is indicated for the treatment of...
Ceftriaxone Sodium and Tazobactam Sodium 3375mg Veterinary Injection
Ceftriaxone is a third-generation cephalosporin antibiotic with broad-spectrum bactericidal activity. It interferes with the bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis and bacterial death. Ceftriaxone is effective against both Gram-positive and Gram-negative bacteria.
Tazobactam is a β-lactamase inhibitor that protects ceftriaxone from degradation by β-lactamase enzymes produced by certain bacteria. This enhances the effectiveness of ceftriaxone against resistant organisms, including those that produce β-lactamase.
The combination of ceftriaxone and tazobactam provides an extended spectrum of activity, especially against resistant pathogens.
Indications: This veterinary injection is indicated for the treatment of a wide range of bacterial infections in animals caused by susceptible organisms, including:
It is effective for use in various animal species, including dogs, cats, and livestock.
Dosage and Administration:
For dogs and cats: Administer the injection either intramuscularly (IM) or intravenously (IV).
Typical dosage: 20-40 mg/kg body weight per day, depending on the severity of the infection.
The injection is typically given once a day, and treatment can continue for 5-10 days or as directed by a veterinarian.
For livestock: The exact dosage should be determined by the attending veterinarian, taking into consideration the species, weight, and condition of the animal.
Contraindications:
Do not use in animals with a known hypersensitivity to ceftriaxone, tazobactam, penicillins, cephalosporins, or any other component of the formulation.
Use with caution in animals with compromised renal or hepatic function.
Warnings:
For veterinary use only. Not intended for animals that will be slaughtered for human consumption.
Overdose may cause adverse effects, such as gastrointestinal upset or neurological symptoms. Follow the veterinarian's guidance on dosage.
This product should only be used under the supervision of a veterinarian.
Side Effects:
Common side effects include:
Gastrointestinal disturbances such as mild diarrhea or vomiting.
Local reactions at the injection site, such as pain, swelling, or irritation.
Rare side effects include:
Allergic reactions such as rashes, fever, or difficulty breathing.
Hematological abnormalities like leukopenia (low white blood cell count) or thrombocytopenia (low platelet count).
Elevations in liver enzymes or signs of liver dysfunction, especially in animals with pre-existing liver conditions.
Renal issues may occur in animals with kidney impairment.
Storage:
Store in a cool, dry place, away from direct sunlight.
Do not freeze the vial.
Once the vial is opened, use within the recommended time frame.
Keep out of reach of children and animals.
Precautions:
Complete the entire course of treatment as prescribed by the veterinarian, even if symptoms improve, to avoid the development of antibiotic resistance.
Monitor kidney and liver function in animals receiving prolonged treatment or those with pre-existing renal or hepatic conditions.
Use this medication only as directed by a veterinarian to prevent misuse or overuse, which could contribute to resistance.