Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic that targets a wide range of both Gram-positive and Gram-negative bacteria. It acts by inhibiting bacterial cell wall synthesis, which leads to cell lysis and bacterial death.
Tazobactam is a β-lactamase inhibitor, which helps prevent the breakdown of ceftriaxone by bacterial enzymes known as β-lactamases. By inhibiting these enzymes, tazobactam extends the spectrum of ceftriaxone, allowing it to remain effective against β-lactamase-producing resistant bacteria.
The combination of ceftriaxone and tazobactam provides enhanced antimicrobial activity, making it an effective treatment for serious infections that may be resistant to other antibiotics.
Indications: This veterinary injection is indicated for ...
Ceftriaxone Sodium and Tazobactam Sodium 2252mg Veterinary Injection
Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic that targets a wide range of both Gram-positive and Gram-negative bacteria. It acts by inhibiting bacterial cell wall synthesis, which leads to cell lysis and bacterial death.
Tazobactam is a β-lactamase inhibitor, which helps prevent the breakdown of ceftriaxone by bacterial enzymes known as β-lactamases. By inhibiting these enzymes, tazobactam extends the spectrum of ceftriaxone, allowing it to remain effective against β-lactamase-producing resistant bacteria.
The combination of ceftriaxone and tazobactam provides enhanced antimicrobial activity, making it an effective treatment for serious infections that may be resistant to other antibiotics.
Indications: This veterinary injection is indicated for the treatment of infections in animals caused by susceptible bacteria, including:
It is suitable for use in dogs, cats, and livestock such as cattle, horses, and swine.
Dosage and Administration:
For Dogs and Cats:
Administer intramuscularly or intravenously.
The standard dosage is 20-40 mg/kg body weight per day, depending on the severity of the infection.
The injection is usually given once a day, and treatment can last from 5 to 10 days or as directed by the veterinarian.
For Livestock:
The dosage should be determined based on the animal's species, weight, and clinical condition, as advised by the veterinarian.
Administer the injection either intramuscularly or intravenously based on veterinary guidance.
Contraindications:
Do not use in animals with known hypersensitivity or allergy to cephalosporins, penicillins, or tazobactam.
Not recommended for use in animals with severe renal or hepatic insufficiency without close veterinary monitoring.
Use with caution in pregnant or lactating animals; consult a veterinarian before use.
Warnings:
For veterinary use only; not intended for animals to be slaughtered for human consumption.
Overdose or improper administration may lead to adverse effects, including gastrointestinal upset, nephrotoxicity, or allergic reactions.
Consult a veterinarian to ensure correct dosage and administration, especially in animals with pre-existing health conditions.
Side Effects:
Common Side Effects:
Mild gastrointestinal symptoms such as diarrhea, nausea, or vomiting.
Injection site reactions such as pain, redness, swelling, or inflammation.
Rare Side Effects:
Allergic reactions: rashes, fever, or more severe symptoms like difficulty breathing.
Hematologic changes: decreased white blood cell or platelet count, leading to increased risk of infection or bleeding.
Liver or kidney abnormalities: liver enzyme elevations or renal dysfunction (more likely in animals with pre-existing conditions).
Storage:
Store the injection in a cool, dry place at temperatures between 15°C and 30°C (59°F to 86°F).
Do not freeze the product.
Once opened, the vial should be used within the recommended timeframe.