Ceftriaxone Sodium & Sulbactam Sodium for Injection 4500mg
Ceftriaxone Sodium and Sulbactam Sodium 4500mg Veterinary Injection is a combination antibiotic used for the treatment of bacterial infections in animals. This formulation combines Ceftriaxone Sodium, a broad-spectrum cephalosporin antibiotic, and Sulbactam Sodium, a β-lactamase inhibitor, to enhance the effectiveness of Ceftriaxone against bacteria that produce β-lactamase, which would normally render the antibiotic ineffective.
Mechanism of Action:
Ceftriaxone Sodium works by inhibiting the synthesis of bacterial cell walls, causing cell lysis and ultimately the death of the bacteria. It is effective against a wide range of Gram-positive and Gram-negative bacteria.
Sulbactam Sodium does not have significant antibiotic activity on its own but acts as a β-lactamase inhibitor. It helps protect Ceftriaxone from degradation by bacterial β-lactamases, thus extending the spectrum of activity of the antibiotic.
Indications:
This combination is indicated...
Ceftriaxone Sodium and Sulbactam Sodium 4500mg Veterinary Injection is a combination antibiotic used for the treatment of bacterial infections in animals. This formulation combines Ceftriaxone Sodium, a broad-spectrum cephalosporin antibiotic, and Sulbactam Sodium, a β-lactamase inhibitor, to enhance the effectiveness of Ceftriaxone against bacteria that produce β-lactamase, which would normally render the antibiotic ineffective.
Mechanism of Action:
Ceftriaxone Sodium works by inhibiting the synthesis of bacterial cell walls, causing cell lysis and ultimately the death of the bacteria. It is effective against a wide range of Gram-positive and Gram-negative bacteria.
Sulbactam Sodium does not have significant antibiotic activity on its own but acts as a β-lactamase inhibitor. It helps protect Ceftriaxone from degradation by bacterial β-lactamases, thus extending the spectrum of activity of the antibiotic.
Indications:
This combination is indicated for the treatment of infections caused by susceptible organisms in animals, such as:
Respiratory tract infections
Urinary tract infections
Soft tissue infections
Skin and wound infections
Bone and joint infections
It is effective against a broad range of pathogens, including:
The dosage of Ceftriaxone Sodium and Sulbactam Sodium 4500mg Veterinary Injection depends on the type of animal, the severity of the infection, and the specific bacterial pathogen involved. It is typically administered through deep intramuscular or slow intravenous injection. The typical dosage is 10-20 mg/kg body weight once a day. Treatment duration can vary depending on the clinical response, but generally, therapy lasts from 5 to 7 days.
Precautions:
The injection should not be used in animals with known hypersensitivity to cephalosporins or penicillins.
Caution is advised when administering to animals with a history of renal or hepatic dysfunction.
It should not be mixed with certain other medications due to the potential for chemical incompatibility.
Side Effects:
Though relatively safe, the following side effects may occur:
Local irritation or pain at the injection site
Diarrhea or gastrointestinal disturbances
Allergic reactions, such as rashes or anaphylaxis (rare)
Changes in blood counts, such as mild leukopenia or thrombocytopenia
Storage:
The product should be stored in a cool, dry place, away from direct sunlight. Once reconstituted, it should be used immediately or stored according to the manufacturer's guidelines.