Introduction: Ceftazidime Pentahydrate is a broad-spectrum antibiotic used in veterinary medicine for the treatment of bacterial infections in animals. It is a third-generation cephalosporin, which is effective against a wide range of Gram-positive and Gram-negative bacteria. The 2000mg dosage form is commonly used for larger animals or more severe infections.
Composition: Each vial of Ceftazidime Pentahydrate contains:
Ceftazidime Pentahydrate 2000mg (equivalent to 1500mg of Ceftazidime)
Pharmacology: Ceftazidime works by inhibiting the synthesis of bacterial cell walls, leading to bacterial cell lysis and death. As a third-generation cephalosporin, it has an extended spectrum of activity, particularly against Pseudomonas aeruginosa, Escherichia coli, Klebsiella species, and Staphylococcus species, among others.
Indications: Ceftazidime Pentahydrate is used for the treatment of bacterial infections in animals, including but not limited to:
Respiratory tract ...
Introduction: Ceftazidime Pentahydrate is a broad-spectrum antibiotic used in veterinary medicine for the treatment of bacterial infections in animals. It is a third-generation cephalosporin, which is effective against a wide range of Gram-positive and Gram-negative bacteria. The 2000mg dosage form is commonly used for larger animals or more severe infections.
Composition: Each vial of Ceftazidime Pentahydrate contains:
Ceftazidime Pentahydrate 2000mg (equivalent to 1500mg of Ceftazidime)
Pharmacology: Ceftazidime works by inhibiting the synthesis of bacterial cell walls, leading to bacterial cell lysis and death. As a third-generation cephalosporin, it has an extended spectrum of activity, particularly against Pseudomonas aeruginosa, Escherichia coli, Klebsiella species, and Staphylococcus species, among others.
Indications: Ceftazidime Pentahydrate is used for the treatment of bacterial infections in animals, including but not limited to:
Respiratory tract infections
Urinary tract infections
Soft tissue infections
Skin and wound infections
Intra-abdominal infections
Septicemia
Bone and joint infections
It is effective against both aerobic and anaerobic bacteria, making it suitable for treating a wide variety of infections.
Dosage and Administration: The dosage of Ceftazidime Pentahydrate varies based on the type of animal and the severity of the infection. Generally, the recommended dosage is:
For large animals (e.g., cattle, horses): 10-20 mg/kg body weight, administered intramuscularly or intravenously.
For small animals (e.g., dogs, cats): 5-10 mg/kg body weight, administered via the same routes.
The frequency of administration is typically once or twice daily, depending on the infection's severity and the veterinarian’s judgment.
Contraindications:
Do not use in animals with known hypersensitivity to cephalosporins or penicillins.
Caution is advised in animals with renal impairment or a history of gastrointestinal disease.
Precautions:
It is important to complete the full course of treatment to avoid bacterial resistance.
Monitor renal function during prolonged use, as cephalosporins are excreted through the kidneys.
Ceftazidime should be used cautiously in animals that are pregnant or lactating unless deemed essential by the veterinarian.
Side Effects: Common side effects may include:
Diarrhea or gastrointestinal upset
Allergic reactions such as rash, fever, or swelling
In rare cases, changes in renal function may occur, especially with prolonged use or high doses.