Ceftazidime Pentahydrate & Tazobacatam for injection 1125mg
Ceftazidime Pentahydrate and Tazobactam 1125mg veterinary injection is a combination antibiotic therapy used in the treatment of bacterial infections in animals. This product combines Ceftazidime, a broad-spectrum cephalosporin antibiotic, with Tazobactam, a beta-lactamase inhibitor. The combination enhances the effectiveness of Ceftazidime against a wider range of bacteria, including those that produce beta-lactamase enzymes, which would otherwise render Ceftazidime less effective.
Mechanism of Action:
Ceftazidime: As a third-generation cephalosporin, it works by inhibiting bacterial cell wall synthesis. It is effective against many Gram-negative bacteria, including Pseudomonas aeruginosa, and has activity against some Gram-positive bacteria as well.
Tazobactam: This beta-lactamase inhibitor prevents the bacterial enzymes (beta-lactamases) from breaking down Ceftazidime. By inhibiting these enzymes, Tazobactam extends the spectrum of activity of Ceftazidime aga...
Ceftazidime Pentahydrate and Tazobactam 1125mg veterinary injection is a combination antibiotic therapy used in the treatment of bacterial infections in animals. This product combines Ceftazidime, a broad-spectrum cephalosporin antibiotic, with Tazobactam, a beta-lactamase inhibitor. The combination enhances the effectiveness of Ceftazidime against a wider range of bacteria, including those that produce beta-lactamase enzymes, which would otherwise render Ceftazidime less effective.
Mechanism of Action:
Ceftazidime: As a third-generation cephalosporin, it works by inhibiting bacterial cell wall synthesis. It is effective against many Gram-negative bacteria, including Pseudomonas aeruginosa, and has activity against some Gram-positive bacteria as well.
Tazobactam: This beta-lactamase inhibitor prevents the bacterial enzymes (beta-lactamases) from breaking down Ceftazidime. By inhibiting these enzymes, Tazobactam extends the spectrum of activity of Ceftazidime against resistant bacterial strains.
Indications:
This injection is used in veterinary medicine to treat various bacterial infections, including:
Respiratory infections in dogs, cats, and other animals.
Urinary tract infections.
Skin and soft tissue infections.
Intra-abdominal infections.
Bone and joint infections.
Septicemia caused by susceptible organisms.
Dosage and Administration:
The dosage of Ceftazidime Pentahydrate and Tazobactam 1125mg veterinary injection is typically based on the weight and condition of the animal. It is administered via intramuscular or intravenous injection, as prescribed by a veterinarian. The general guideline is:
Small animals: 1-2 mg per kg body weight, administered every 12 to 24 hours.
Larger animals: Higher doses may be required, and the veterinarian will determine the appropriate regimen.
Side Effects:
While generally well-tolerated, some animals may experience mild side effects, such as:
Allergic reactions (e.g., rash, swelling).
Gastrointestinal disturbances (vomiting, diarrhea).
Local reactions at the injection site (pain, swelling).
Rarely, more serious effects such as nephrotoxicity or neurotoxicity.
Precautions:
Use with caution in animals with a history of hypersensitivity to beta-lactam antibiotics.
Care should be taken when administering to animals with impaired renal function.
Not recommended for use in pregnant or lactating animals unless clearly necessary, as the effects on fetal development are not well-documented.