Cefpirome Sulphate and Sulbactam Dry injection Uses, and Manufacturing Process

Manufactured by R K Lifecare INC, India

At R K Life Care INC. We are a trusted manufacturer of Cefpirome Sulphate and Sulbactam Dry Injection in India, committed to providing world-class injectable formulations for both human and veterinary use. Our advanced pharmaceutical manufacturing facility is equipped with state-of-the-art technology, which ensures that each product meets international quality, purity, and safety standards.

About Cefpirome Sulphate and Sulbactam

Cefpirome Sulphate is a fourth-generation cephalosporin antibiotic known for its broad-spectrum activity against both gram-positive and gram-negative bacteria, including resistant strains such as Pseudomonas aeruginosa and Enterobacter species. It works by inhibiting bacterial cell wall synthesis, leading to cell death.

Sulbactam is a beta-lactamase inhibitor that enhances the efficacy of cefpirome by preventing bacterial enzymes (beta-lactamases) from degrading the antibiotic. This combination broadens the antibacterial spectrum and ensures high clinical efficacy against resistant infections.

Cefpirome Sulphate and sulbactam together form a synergistic combination used for the effective treatment of serious infections.

Uses of Cefpirome Sulphate and Sulbactam Dry Injection

Cefpirome Sulphate and sulbactam dry injection is widely prescribed in hospitals and health care facilities to treat serious bacterial infections, including:

• Respiratory tract infections: pneumonia, bronchitis, and lung abscesses.
• Urinary tract infections (UTIs): complicated and hospital-acquired infections.
• Skin and soft tissue infections: cellulitis, wound infections, and abscesses.
• Intra-abdominal infections: peritonitis, biliary tract infections, and sepsis.
• Bone and joint infections: osteomyelitis and septic arthritis.
• Gynecological and pelvic infections: endometritis, pelvic inflammatory disease.
• Postoperative and hospital-acquired infections: where resistant bacteria are suspected.

Dosage and administration are determined by a qualified healthcare professional based on the type and severity of the infection as well as the patient's condition.

Manufacturing Process of Cefpirome Sulphate and Sulbactam Dry Injection at R K Lifecare INC

At RK Lifecare Inc., the manufacturing process of Cefpirome Sulphate and Sulbactam Dry Injection follows Good Manufacturing Practice (GMP) and WHO-plant quality standards to ensure efficacy, consistency, and safety.

1. Raw Material Procurement and Quality Testing

• High-purity Cefpirome Sulphate and sulbactam sodium are sourced from certified and approved vendors.
• Each batch undergoes rigorous quality testing for identity, potency, pH, and impurity levels before entering production.

2. Sterile Blending and Mixing

• Active pharmaceutical ingredients (APIs) are precisely weighed and mixed in a controlled environment, under aseptic conditions.
• The mixing process ensures uniform distribution of both components, maintaining their potency.

3. Sterile Filling

• This sterile blended powder is filled into Type I glass vials using automated filling lines.
• The filling process is performed in a Class 100 cleanroom to prevent microbial contamination.

4. Lyophilization (Freeze Drying)

• The filled vials are then subjected to lyophilization, a process that removes moisture while maintaining the product's stability and effectiveness.
• This results in a stable, dry powder suitable for long-term storage.

5. Sealing and Packaging

• Vials are sealed with aluminum flip-off seals and rubber stoppers to maintain sterility.
• Each batch is packaged in sterile, tamper-proof boxes with appropriate labeling, including dosage amount, composition, and manufacturing details.

6. Quality Control and Assurance

• Each batch undergoes extensive in-process and final product testing, including:

  • Sterility test

  • Particulate matter test

  • Assay of Cefpirome and Sulbactam

  • pH and moisture content test

  • Stability and shelf-life studies

• The quality assurance team ensures that only products meeting international standards are released into the market.

Why Choose R K Lifecare INC. for Cefpirome Sulphate and Sulbactam Injection Manufacturing

• WHO-GMP and ISO-certified manufacturing facility
• Strict adherence to regulatory guidelines for sterile injections
• Highly skilled technical team with decades of industry experience
• Custom manufacturing and contract manufacturing (third-party) options available
• Guaranteed product stability, safety, and efficacy

Conclusion

Cefpirome Sulphate and sulbactam dry injection is a powerful, broad-spectrum antibiotic combination used in the treatment of serious bacterial infections. At RK Lifecare Inc., we ensure that each vial produced reflects our dedication to quality, safety, and innovation in injection manufacturing.

Our commitment to excellence makes us one of the most trusted manufacturers of Cefpirome Sulphate and Sulbactam Injection in India, supplying hospitals, healthcare institutions, and pharmaceutical distributors in both domestic and international markets.

R K Lifecare INC is a leading manufacturer of Cefpirome Sulphate and Sulbactam Dry Injection in India, ensuring high-quality, safe, and effective formulations.