Ceftriaxone is a third-generation cephalosporin antibiotic with broad-spectrum activity against both Gram-positive and Gram-negative bacteria. It works by binding to bacterial penicillin-binding proteins (PBPs) on the bacterial cell wall, inhibiting cell wall synthesis, and leading to bacterial cell lysis and death. Ceftriaxone is highly effective against a wide range of pathogens, including Escherichia coli, Staphylococcus spp., Streptococcus spp., and many other common bacteria.
It is effective against both aerobic and anaerobic organisms, making it a versatile option for treating various infections.
Indications: Ceftriaxone Sodium 1000mg Veterinary Injection is used for the treatment of bacterial infections in animals, including:
Ceftriaxone is a third-generation cephalosporin antibiotic with broad-spectrum activity against both Gram-positive and Gram-negative bacteria. It works by binding to bacterial penicillin-binding proteins (PBPs) on the bacterial cell wall, inhibiting cell wall synthesis, and leading to bacterial cell lysis and death. Ceftriaxone is highly effective against a wide range of pathogens, including Escherichia coli, Staphylococcus spp., Streptococcus spp., and many other common bacteria.
It is effective against both aerobic and anaerobic organisms, making it a versatile option for treating various infections.
Indications: Ceftriaxone Sodium 1000mg Veterinary Injection is used for the treatment of bacterial infections in animals, including:
It is effective in treating both simple and complicated infections, and is commonly used in dogs, cats, and livestock.
Dosage and Administration:
For dogs and cats:
Intramuscular (IM) or Intravenous (IV) administration.
Typical dosage: 20-40 mg/kg body weight once a day.
The dosage may be adjusted depending on the severity of the infection and the specific condition of the animal.
The treatment duration can range from 5 to 10 days, depending on the infection's response and severity.
For livestock:
The dosage for livestock (cattle, sheep, pigs, etc.) should be determined by a veterinarian based on the animal's weight and the severity of the infection.
It is important to follow the veterinarian’s instructions on dosage and administration to ensure optimal effectiveness and minimize the risk of side effects.
Contraindications:
Do not use in animals with a known hypersensitivity to cephalosporins, penicillins, or other β-lactam antibiotics.
Use with caution in animals with pre-existing renal or hepatic impairment, as adjustments may be needed.
Warnings:
For veterinary use only – not intended for use in animals that will be slaughtered for human consumption.
Overdose or improper administration can result in adverse effects, including gastrointestinal symptoms like diarrhea, nausea, or vomiting.
If allergic reactions such as rashes, fever, or difficulty breathing occur, the treatment should be discontinued immediately, and appropriate emergency measures should be taken.
Side Effects:
Common side effects may include:
Mild gastrointestinal upset (diarrhea, vomiting)
Local reactions at the injection site, such as pain, swelling, or inflammation.
Rare side effects may include:
Allergic reactions such as skin rashes, fever, or anaphylaxis.
Hematological changes such as leukopenia, thrombocytopenia, or anemia.
Liver enzyme elevations or renal dysfunction, particularly in animals with compromised kidney or liver function.
Storage:
Store the vial in a cool, dry place, away from direct sunlight.
Do not freeze. Once opened, use within the recommended period.
Keep out of reach of children and animals.
Precautions:
Complete the entire course of treatment as prescribed by the veterinarian, even if symptoms improve before the full treatment period ends. Premature discontinuation may lead to antibiotic resistance.
Monitor the animal's clinical condition during treatment, especially for signs of adverse effects.
Regularly check kidney and liver function in animals with pre-existing conditions.