Ceftriaxone Sodium & Sulbactam Sodium for Injection 3000mg
Ceftriaxone is a broad-spectrum cephalosporin antibiotic that works by inhibiting bacterial cell wall synthesis, leading to cell death. It is particularly effective against Gram-positive and Gram-negative bacteria, making it a preferred option for many bacterial infections. It is typically used for infections such as pneumonia, urinary tract infections, skin infections, and surgical prophylaxis.
In veterinary medicine, ceftriaxone is administered for the treatment of systemic infections in animals, particularly when other antibiotics may not be as effective. The sodium salt form allows it to be easily injected, often in animals like dogs, cats, and livestock.
Sulbactam Sodium
Sulbactam is a beta-lactamase inhibitor that works by inhibiting the enzymes produced by certain bacteria to deactivate beta-lactam antibiotics. When combined with ceftriaxone, it extends the antibiotic’s spectrum of action, making it effective against bacteria that produce beta-lactamase, an en...
Ceftriaxone is a broad-spectrum cephalosporin antibiotic that works by inhibiting bacterial cell wall synthesis, leading to cell death. It is particularly effective against Gram-positive and Gram-negative bacteria, making it a preferred option for many bacterial infections. It is typically used for infections such as pneumonia, urinary tract infections, skin infections, and surgical prophylaxis.
In veterinary medicine, ceftriaxone is administered for the treatment of systemic infections in animals, particularly when other antibiotics may not be as effective. The sodium salt form allows it to be easily injected, often in animals like dogs, cats, and livestock.
Sulbactam Sodium
Sulbactam is a beta-lactamase inhibitor that works by inhibiting the enzymes produced by certain bacteria to deactivate beta-lactam antibiotics. When combined with ceftriaxone, it extends the antibiotic’s spectrum of action, making it effective against bacteria that produce beta-lactamase, an enzyme that typically makes them resistant to cephalosporins.
The combination of ceftriaxone and sulbactam is especially useful for treating infections caused by resistant bacteria such as Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. It’s also useful in treating mixed infections, where multiple bacterial species may be involved.
Veterinary Applications
In veterinary use, the injection is typically administered intramuscularly or intravenously, depending on the severity and type of infection. It is often used to treat:
The exact dosage varies based on the animal's species, weight, and severity of the infection. For example, dogs and cats may receive 10-20 mg/kg body weight, typically administered once or twice a day. It is important to follow the veterinarian's prescribed dosage to avoid complications, as overuse can contribute to antibiotic resistance.
Safety and Side Effects
Common side effects may include mild pain or swelling at the injection site, allergic reactions, or gastrointestinal upset in animals. Rare but more serious reactions can occur, so it's important to monitor animals closely after administration, especially if they have known allergies to cephalosporins or beta-lactam antibiotics.
In general, the combination of ceftriaxone and sulbactam is regarded as safe for use in veterinary practice, though it should be used cautiously in animals with renal or hepatic impairments.