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Cefpirome Sulphate for injection 1000mg

Composition: Each vial contains Cefpirome Sulphate 1000 mg, a broad-spectrum cephalosporin antibiotic, formulated for veterinary use.

Indications: Cefpirome Sulphate is used in the treatment of a variety of bacterial infections in animals, particularly in cases involving susceptible Gram-positive and Gram-negative bacteria. It is commonly prescribed for infections such as:

  • Respiratory tract infections
  • Skin and soft tissue infections
  • Urinary tract infections
  • Septicemia
  • Infections of the digestive tract
  • Infections following surgery or injury

Mode of Action: Cefpirome is a fourth-generation cephalosporin antibiotic. It works by inhibiting bacterial cell wall synthesis, leading to the disruption of cell wall integrity, which ultimately results in bacterial cell death. Cefpirome is effective against both Gram-positive and Gram-negative bacteria, including some strains resistant to earlier generations of cephalosporins.

Dosage and Administration: The recommended dosage of Cefpirome Sulphate 1000 mg varies depending on the type of animal and severity of the infection. Typically, it is administered as an intramuscular or intravenous injection:

  • For cattle, horses, and swine: 1 to 2 mg/kg body weight, administered every 12 hours.
  • For smaller animals like dogs and cats: The dosage is adjusted based on the specific infection and animal's weight, typically ranging from 1 to 2 mg/kg body weight every 12 to 24 hours.

The exact dosage and frequency should be determined by a veterinarian.

Contraindications: Cefpirome should not be used in animals with known hypersensitivity to cephalosporins or penicillins. It is also contraindicated in animals with a history of severe allergic reactions to beta-lactam antibiotics.

Precautions:

  • Use with caution in animals with impaired renal function as dosage adjustments may be necessary.
  • Always follow the prescribed dosage to prevent the development of bacterial resistance.
  • Avoid use in pregnant or lactating animals unless specifically recommended by a veterinarian.

Side Effects: Possible side effects include:

  • Local irritation or discomfort at the injection site
  • Allergic reactions such as rash, fever, or anaphylaxis
  • Gastrointestinal disturbances such as nausea or diarrhea (though rare) If any adverse effects are observed, treatment should be discontinued and veterinary consultation sought.

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